It'd be useful to know what you have already on the computer side, and what you hope to achieve as there are many options.

McIntosh seem (not too familiar with them tbh) to be going for the standalone market i.e. you buy one of their servers, you chuck a disc in it, it rips it and you play it back via the server etc.

IMO you'll pay a HUGE premium for this sort of thing.

A cheaper option is often a PC or Mac, coupled with a streaming player such as a Squeezebox or Airport Express, into a DAC.

I'd say control is as big of an issue as sound quality with this kind of thing - for example a Squeezebox comes with a remote control and an LED display on the streamer itself so you can have your computer in another room and select tracks from a remote in your listening environment.