Brad, absolutely. For example, my 'watch DVD' activity turns on the DVD player, turns on the 565, sets the 565 to DVD input, turns on the plasma, goes to the right AV channel on the plasma, and switches the IScan to the DVD video input. All one button.

Main system: 818v3, 861v6, HD621, Oppo 103D, DSP8000PP, DSP7200SE HC, DSP3200, SGR Sub
Family room: HD621, 861v6, DSP5200 L/C/R
Headphones: Schiit Mjolnir v1, Sennheiser HD800; (office) iFi iDSDPro, Focal Elegia