No it does not. It's a 2 channel only end point in Roon. The other option from downmix is channel map which would only use L and R from multi channel.
Speakerlink is 2 channel only as well
I use my HD621 via HDMI from roon core as my multi channel end point.
Main system:G65, 218, HD621 2 x DSP5200SE, 1 x DSP5200HCSE, 2 x DSP5200SL, Power Sound Audio S1512, DSP Anti-Mode 2.0 Dual core, NuPrime H16AES, 518, Dune HD Homatics Box R 4K Plus running CoreElec 21.3, Oppo 103D and SqueezeTouch. Atmos, MQA and Trifield! 
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