I think it comes down to room accommodations + budget. Im not sure the 5000s will play much deeper than the 33s so that you could set the 5000s to large whereas the 33s have to be set to small. Therefore I would go with the more economical 33s. I would recommend full range speakers all around as the optimal setup, but this is not realistic for everyone. JMHO.

best regards,
Jerry

Best regards,
Jerry
Main System: 861v6, DSP8000s in corners, DSP7000s Center and Sides, 1-9 humans.