Today I placed my ER inline directly out of my Roon Server in my Network closet, the SQ was different but still good. Then I changed it to input directly into the ENO at my system end, and it sounds better. It seems that it is true, these "filters" do seem to perform best when closest to the streamer.
I am not sure if I like it better in or out of the mix yet. I agree with Clemburt, it may somehow be too much. I'll listen more at various volume levels and do the comparison. My preference, of course, is to install as few devices as needed, especially as Jeremy said, if they add additional cables and heat. The ENO seems to be burning in nicely and sounds great.