Would need to be set up as master speaker obviously and typed to accept non-Meridian input (and you’d need at least a MSR remote to do that) but any typical digital source putting out a typical digital audio signal - CD playing a standard 16/44.1 disc - would be just fine. See Duncan’s Meridian Info at top of page for appropriate manual.

M#1: Bluesound Node (N130)>DSP3100 + Analog Sub
M#2: WiiM Pro > DSP5000