What is the latest consensus- is it safe to update to the latest QNAP firmware?

I am running 4.2.0 on a TS-251 with core and store for Sooloos with no problems and want to update but will only do it if most people are not having issues.

Tim, did you get your system problems resolved?

My gear: Trinnov CI, 271, 8000.1(SEs), 7200.1 HC (SE), 320s, 3200s, Seaton F18 subs, MS200 (2nd zone), 218, 210.
Other: JVC RS-4100 projector, Lumagen Pro Radiance, Panamorph DCR anamorphic lens, Stewart G4 130 screen, Kaleidescape Strato K, Rvolution 4K player and Zapitti NAS, Oppo BDP-203,Roon Nucleus