Try:
DSP RS232 Control Note carefully:
Some (configuration commands) only affect the connected speaker
The non-volatile commands will be writing to flash memory - so will have a finite number of writes before it won't write no more - i.e. make sure you are not writing continuously from an automation system and don't set anything you don't want remembering.
There's a command to list the non-volatile settings as well - might be useful checking each speaker in turn to make sure they match if you've been poking around.
Matt.