I'm sure you know this already, but your MS200 will always sound better than any software running on a Mac in Exclusive Mode??... and especially true if the Mac is also running as a Plex Server.
Thanks Ronnie.
I agree, but going MS200 via analogue into the Prime rather defeats the object of being able to have all that lovely M digital stuff going on in the Prime, particularly as the MS200 route will not (as far as I'm aware) get me any MQA compatibility whereas the iMac into the Prime via USB will.
The Plex and Roon servers are being deliberately running elsewhere.