I'm using Chrome on my MacPro in the office and then USB to an AC200, and in the Lounge MacBookPro optical out into 861 until full intergration.

Very pleased so far, very good database, still evaluating it versus MS200 and ID41 but seems pretty close.

#1 861v8+ID41, DSP7200SE, DSP5200HCSE, DSP33, DSW, MD600.
#2 MS200, Sennheiser Momentums hd400
#3 818v3, Genelec 1030a's