It all depends on the network protocol Meridian uses.
If this is TCP, you should have not find any differences. If they use UDP, keep the MC200 as close to the source as possible.
UDP does use a checksum, but does not require the package to be resend. In case of a corrupted package it simply gets dropped.
Meridian use UDP for audio but maintain a TCP handshake channel at less granular level that can deal with retransmission of dropped packets.
That said, UDP is pretty robust in a hard wired LAN (as M recommend ) of any length (within spec) especially as M have control over the hardware/software/stack/configuration. Different story when it gets routed or transmitted over wifi when you have more than dropped packets to contend with.