I replaced a motherboard and dead battery in a Source:One and it worked fine afterwards without doing anything else.
If a motherboard is replaced you will have to tell Meridian you changed boards from the one with your current MAC address to a new board and MAC address or else it won't log into the Meridian cloud service. Without that it won't update unless you re-register it.
It will work without doing that but it just won't get the next software update. I paid a premium partner for their time to help me register the MAC address.